Rational Reprogramming of Cellular States by Combinatorial Perturbation

Author
Affiliation

Jialei Duan

UT Southwestern Medical Center

Published

Sat Aug 12, 2023 00:21:44-05:00

Abstract

Reprogram-Seq leverages organ-specific cell atlas data with single-cell perturbation and computational analysis to predict, evaluate, and optimize TF combinations that reprogram a cell type of interest.


Workflow

Rational Reprogramming of Cellular States by Combinatorial Perturbation


Citation

Jialei Duan#, Boxun Li#, Minoti Bhakta#, Shiqi Xie, Pei Zhou, Nikhil V. Munshi*, Gary C. Hon* (2019). Rational Reprogramming of Cellular States by Combinatorial Perturbation. Cell Rep. 27, 3486–3499.e6.
DOI: 10.1016/j.celrep.2019.05.079