Miscellaneous

Abstract

Human blastoids provide a readily accessible, scalable, versatile and perturbable alternative to blastocysts for studying early human development, understanding early pregnancy loss and gaining insights into early developmental defects.

from datetime import datetime
datetime.today().strftime("%Y-%m-%d %H:%M:%S")

'2022-09-25 00:38:50'

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In this manuscript, several transcriptome data sets generated by different technologies were included. To minimize platform and processing differences, raw fastq files of public datasets using the Illumina sequencing platform were downloaded and re-processed.

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Related publications:

• Yanagida, A., Spindlow, D., Nichols, J., Dattani, A., Smith, A., and Guo, G. (2021). Naive stem cell blastocyst model captures human embryo lineage segregation. Cell Stem Cell 28, 1016–1022.e4.
• Fan, Y., Min, Z., Alsolami, S., Ma, Z., Zhang, E., Chen, W., Zhong, K., Pei, W., Kang, X., Zhang, P., et al. (2021). Generation of human blastocyst-like structures from pluripotent stem cells. Cell Discov 7, 81.
• Sozen, B., Jorgensen, V., Weatherbee, B.A.T., Chen, S., Zhu, M., and Zernicka-Goetz, M. (2021). Reconstructing aspects of human embryogenesis with pluripotent stem cells. Nat. Commun. 12, 5550.
• Kagawa, H., Javali, A., Khoei, H.H., Sommer, T.M., Sestini, G., Novatchkova, M., Scholte Op Reimer, Y., Castel, G., Bruneau, A., Maenhoudt, N., et al. (2021). Human blastoids model blastocyst development and implantation. Nature 1–9.

Citation

BibTeX citation:

@article{yu,
  author = {Leqian Yu and Yulei Wei and Jialei Duan and Daniel A.
    Schmitz and Masahiro Sakurai and Lei Wang and Kunhua Wang and Shuhua
    Zhao and Gary C. Hon and Jun Wu},
  editor = {},
  publisher = {Nature Publishing Group},
  title = {Blastocyst-Like Structures Generated from Human Pluripotent
    Stem Cells},
  journal = {Nature},
  volume = {591},
  number = {7851},
  pages = {620 - 626},
  date = {},
  url = {https://doi.org/10.1038/s41586-021-03356-y},
  doi = {10.1038/s41586-021-03356-y},
  langid = {en},
  abstract = {Human blastoids provide a readily accessible, scalable,
    versatile and perturbable alternative to blastocysts for studying
    early human development, understanding early pregnancy loss and
    gaining insights into early developmental defects.}
}

For attribution, please cite this work as:

Leqian Yu, Yulei Wei, Jialei Duan, Daniel A. Schmitz, Masahiro Sakurai, Lei Wang, Kunhua Wang, Shuhua Zhao, Gary C. Hon, and Jun Wu. n.d. “Blastocyst-Like Structures Generated from Human Pluripotent Stem Cells.” Nature 591 (7851): 620–26. https://doi.org/10.1038/s41586-021-03356-y.